专利名称：VITAMIN E COMPOSITION发明人：TAKAHASHI MASATO,OHASHI
KOICHI,NEMOTO MASAMI,YAMAGUCHIHIROSHI
申请号：JP10664488申请日：19880428公开号：JPH01279829A公开日：19891110
摘要：PURPOSE:To obtain the subject composition, good in dispersibility in gastricjuice, etc., in internal use, improved in absorbability, and effective in preventing formationof peroxylipids, etc., by blending vitamin E with a polyoxyethylene sorbitan ester andsorbitan dioleate in a specific proportion. CONSTITUTION:A vitamin E compositionobtained by blending a polyoxyethylene sorbitan ester with sorbitan dioleate which areactive ingredients respectively at 9:1-6:4 blending ratio therein. For example,
polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monopalmitate, etc.,are cited as the polyoxyethylene sorbitan ester. The blending ratio of the vitamin E is 0.8-1.2 if the total blended amount of the polyoxyethylene sorbitan ester and sorbitandioleate is 1. In preparing a pharmaceutical, polyhydric alcohols, such as polyethyleneglycol, may be added in an amount of 5-10 times based on the total pharmaceutical.
申请人：TAISHO PHARMACEUT CO LTD
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